Figure 3.

B7-H1 is required for ERCs to alleviate transplant vasculopathy. (a) Histology of the transplanted aorta in B6 recipients. Grafts were collected at posttransplant day 40 and evaluated by H&E staining of paraffin sections. Pathological changes from the (A) untreated group, (B) anti-B7-H1 mAb-pretreated ERC group, (C) ERC-treated group, and (D) IFN-γ-pretreated group were presented (n = 6). The black arrows indicated the intimal limits (100x magnification). (b) The intimal thickness of the grafts in each group. Values were presented as mean ± SEM; statistical analysis was done by one-way ANOVA followed by the LSD test, n = 6.