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Maternal folic acid supplementation altered one carbon metabolism in offspring. Dams were fed as described in Figure 1. (A) Brain Hcy concentration in pups; (B) Brain SAM concentration in pups; (C) Brain SAH concentration in pups; (D) Methylation potential (SAM:SAH ratio) in brain tissue of pups. * p < 0.05 compared with DD group. # p < 0.05 compared with ND group. Data are expressed as mean ± SD for n = 10 pups/group (same pups as Figure 2).
