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Maternal folic acid supplementation increased the expression of DNMTs in offspring brains. Dams were fed as described in Figure 1. (A–C) mRNA expression of DNMT1, 3a and 3a in brain tissue of pups; (D–F) Protein expression of DNMT1, 3a and 3b in brain tissue of pups. * p < 0.05 compared with DD group. # p < 0.05 compared with ND group. & p < 0.05 compared with FD-S group. Data are expressed as mean ± SD for n = 10 pups/group (same pups as Figure 2).
