Table 6.

EF1 for Consensus Methods and Best Individual Performance^a

Target	Best	Consensus (+HYBRID)						Consensus (−HYBRID)
		BCS	MVC	Mean	Med	Max	Min	BCS	MVC	Mean	Med	Max	Min
ADRB1	25	31	27	28	24	21	19	22	24	25	23	19	20
DRD3	10	13	7	12	11	4	11	12	5	10	9	4	8
GRIA2	47	49	46	45	33	24	28	41	31	31	25	22	18
BRAF	29	29	23	22	15	21	6	22	20	17	11	19	4
CDK2	30	35	27	29	24	23	14	25	21	22	20	17	15
PLK1	10	8	8	5	4	7	1	4	4	3	3	5	0
SRC	7	7	9	7	6	6	5	8	9	6	6	7	4
FABP4	32	34	32	32	32	13	6	32	32	26	30	11	6
ESR1	37	38	37	34	34	32	16	37	36	32	33	31	14
ESR2	40	35	34	31	28	26	9	32	30	27	23	26	7
ACE	24	33	30	30	26	19	13	32	28	28	24	19	13
GLCM	35	37	30	30	28	19	19	22	22	22	19	15	19
HDAC8	32	45	46	46	41	20	35	32	38	38	34	16	32
HIVNT	15	19	21	17	11	13	10	15	18	16	13	12	11
PDE5A	31	32	28	26	26	19	13	24	23	23	24	14	12
PTN1	26	35	37	35	32	30	20	35	32	32	28	27	18
ADA 17	17	19	17	16	17	11	4	14	16	15	15	10	3
FA10	27	26	30	33	30	23	19	25	29	32	28	22	18
HIVPR	15	19	16	18	18	9	15	17	15	17	15	9	15
MMP13	30	34	25	26	24	20	18	23	20	22	21	16	15
TRY1	39	33	31	28	27	24	18	30	30	28	24	23	16
mean	27	29	27	26	23	18	14	24	23	22	20	16	13
std. dev.	11	11	11	11	10	8	8	10	9	9	8	7	7

^aColors represent a 3-point gradient from worst (red) to best (green). “Best” indicates the best performance across docking programs.

BCS = boosting consensus score, MVC = mean-variance consensus.