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. Author manuscript; available in PMC: 2018 Mar 28.
Published in final edited form as: Eur J Neurosci. 2015 Aug 6;42(6):2312–2321. doi: 10.1111/ejn.13010

Figure 2. Development of spontaneous network activity in vitro.

Figure 2

A–B) Each voltagegram represents ten randomly selected neurons recorded at an early developmental age (DIV 6–10) - each row represents a 40 sec recording from one neuron. Left panels: neurons from WT circuits; right panels: neurons from Fmr1−/y circuits. The trace above voltagegrams presents the same trace as the first row of the voltagegram.

C–D) Same as in AB but from mature circuits (DIV 21–30).

E) Different quantitative measures of spontaneous network activity. A 40-second voltage trace of spontaneous activity of a pyramidal neuron.