Table 1.

RBC antigen matching and alloimmunization worldwide

Study	N	Age of Patients	Country	Total Units Transfused	Matching	Patient % w/AlloAbs
Orlina et al. 1978	50	Adult	US*	N/A	ABO, D	36%
Coles et al. 1981	72	Pediatric†, Adult	US	N/A	ABO, D	23.6%
Sarnaik et al. 1986	245	Pediatric, Adult	US	N/A	ABO, D	7.8%
Ambruso et al. 1987	12	Pediatric, Adult	US	492	ABO, D	75%
Cox et al. 1988	73	Adult	US	N/A	ABO, D	30%
Rosse et al. 1990	1044	Pediatric, Adult	US	N/A	ABO, D	27%
Vichinsky et al. 1990	107	Pediatric, Adult	US	1,711	ABO, D	30%
Moreira Jr et al. 1996	85	Pediatric, Adult	Brazil	1,300	ABO, D	12.9%
Aygun et al. 2002	140	Pediatric, Adult	US	3,239	ABO, D	37%
Castro et al. 2002	351	Adult	US	8,939	ABO, D	29%
Sakhalkar et al. 2005	387	Pediatric, Adult	US	14,263	ABO, D	31%
Bashwari. 2007	350	Pediatric, Adult	Saudi Arabia	N/A	ABO, D	13.7%
Ameen et al. 2009	110	Pediatric, Adult	Kuwait	N/A	ABO, D	65.5%
Natukunda et al. 2010	428	Pediatric, Adult	Uganda	3366	ABO, D	6.1%
Aly et al. 2012	42	Pediatric, Adult	Egypt	N/A	ABO, D	21.4%
Vinchinsky et al. 2001	61	Pediatric	US	1,830	Limited (C, E, K)	11%
Sakhalkar et al. 2005	113	Pediatric, Adult	US	2,354	Limited (C, E, K)	5%
Ameen et al. 2009	123	Pediatric, Adult	Kuwait	N/A	Limited (C, E, K)	23.6%
O’Suoji et al. 2013	180	Pediatric	US	N/A	Limited (C, E, K)	14%
Chou et al. 2013	182	Pediatric, Adult	US	44,482	Limited (C, E, K)‡	44%
DeBaun et al. 2014	90	Pediatric	US	3,236	Limited (C, E, K)	4.5%
Tahhan et al. 1994	40	Pediatric, Adult	US	608	Extended matching¥	0%
Lasalle-Williams et al. 2011	99	Pediatric, Adult	US	6,946	Extended matching§	7%

^*US = United States; N/A, not available;

^†Pediatric is defined as any patient ≤ 18 years of age;

^‡Limited matched units from African American donors;

^¥C/c, E/e, K, Fy^a, Fy^b, S;

^§C/c, E/e, K, Fy^a, Jk^a, Jk^b.

N/A = not available.