Table 1.

Annotation for the 5 genes differentially methylated in 8 of 11 matched pairs, as determined by genome-wide DNA methylation analysis. *The official gene symbol, gene name and stated function were retrieved from the NCBI Gene database (accessed September 2015). **The absolute β-value difference range is the minimum to the maximum value of the individual absolute β-value differences for each differentially methylated CpG.

Gene symbol*	Absolute β-value difference range**	Gene name*	Functional summary
COPS8	0.05–0.84	Constitutive photomorphogenic homolog subunit 8	Regulator of multiple signaling pathways
PIK3R5	0.02–0.82	Phosphoinositide-3-kinase, regulatory subunit 5	Cell growth, proliferation, differentiation, motility, survival, and intracellular trafficking
HAAO	0.02–0.77	3-hydroxyanthranilate 3,4-dioxygenase	Catalyzes the synthesis of quinolinic acid (QUIN), which is an excitotoxin that may participate in the pathogenesis of neurologic and inflammatory disorders
CCDC124	0.01–0.79	Coiled-coil domain containing 124	Cell cycle, cell division
C5orf34	0.01–0.77	Chromosome 5 open reading frame 34	Unknown, but sequence is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and zebrafish