Table 1.
Demographic and clinical characteristics of SCCHN patients
| Total | |||||
|---|---|---|---|---|---|
| Hsp70 scores 0–2 | % | Hsp70 scores 3–4 | % | p‐Value | |
| Gender | 0.922 | ||||
| Male | 65 | 44.8 | 57 | 39.3 | |
| Female | 12 | 8.3 | 11 | 7.6 | |
| Age (mean ± SD) | 56.3 ± 10.3 | 58.1 ± 7.7 | 0.232 | ||
| Tumor site | 0.318 | ||||
| Oropharynx | 44 | 30.3 | 43 | 29.7 | |
| Hypopharynx | 9 | 6.2 | 11 | 7.6 | |
| Oral cavity | 24 | 16.6 | 14 | 9.6 | |
| pT stage | 0.960 | ||||
| 1–2 | 49 | 33.7 | 43 | 29.7 | |
| 3–4 | 28 | 19.3 | 25 | 17.3 | |
| pN stage | 0.020* | ||||
| 0–1 | 24 | 16.6 | 10 | 6.8 | |
| 2–3 | 53 | 36.5 | 58 | 40.1 | |
| Grading | 0.771 | ||||
| 1 | 2 | 1.3 | 2 | 1.3 | |
| 2 | 41 | 28.3 | 33 | 22.8 | |
| 3 | 34 | 23.5 | 33 | 22.8 | |
| Resection margin (ECE) | 0.717 | ||||
| R0 | 43 | 29.7 | 40 | 27.5 | |
| R1 | 34 | 23.4 | 28 | 19.4 | |
| HPV16 DNA | 0.277 | ||||
| Positive | 25 | 17.3 | 28 | 19.3 | |
| Negative | 52 | 35.8 | 40 | 27.6 | |
| p16 | 0.271 | ||||
| Positive | 26 | 17.9 | 29 | 20.1 | |
| Negative | 51 | 35.2 | 39 | 26.8 | |
| p53 | 0.055 | ||||
| Positive | 37 | 25.6 | 22 | 15.1 | |
| Negative | 40 | 27.5 | 46 | 31.8 | |
| Smoking history | 0.570 | ||||
| Yes | 68 | 46.9 | 62 | 42.7 | |
| No | 9 | 6.2 | 6 | 4.2 | |
| CD56+ NK cell infiltration | |||||
| Low | 15 | 28.8 | 13 | 28.3 | |
| High | 37 | 71.2 | 33 | 71.7 |
Bold values marked with * present p‐values <0.05 and are considered as statistically significant.