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. 2017 Oct 30;31(2):185–192. doi: 10.1007/s10278-017-0030-2

Table 2.

Example report Impression section, with corresponding manual and cTAKES annotations. There are three manual annotations (italicized) and four cTAKES (three in the signs/symptoms type class and one in the disease/disorder type class). We count two of these as true positives: cTAKES found a perfect match for “pulmonary nodules” and a partial match for “improving atelectasis”; one false negative: “fluid collection” from the manual annotations set not flagged by cTAKES; and one false positive: cTAKES annotated “follow-up” as a sign/symptom, but this has no overlap with any manual annotation. Note that cTAKES generated two overlapping annotations, “pulmonary nodules” as a sign/symptom, and “nodules” as a disease/disorder. Accounting for this can get confusing. It is not accurate to include this string as a true positive since the overlapping phrase “pulmonary nodules” is already counted as a true positive. Including “nodules” would artificially inflate the number of true-positive matches. It is also not fair to include it as a false positive, since it is a partial match to a gold-standard annotation. Finally, it is not fair to count it as a false negative in the context of the manual annotation task, which did not ask the manual annotators to differentiate such semantic nuances. We excluded these by defining false-positive matches as only those cTAKES matches that had no overlap with a gold-standard annotation, without regard to polarity of the match. A match with incorrect polarity is already accounted for as a false negative

Example Impression section:
 1. Indeterminate fluid collection in the left lower quadrant.
 2. 9 and 5 mm pulmonary nodules at the left lung base, now better visualized due to improving atelectasis. Recommend 3 month follow-up.
Manual annotations:
 1. Indeterminate fluid collection in the left lower quadrant.
 2. 9 and 5 mm pulmonary nodules at the left lung base, now better visualized due to improving atelectasis. Recommend 3 month follow-up.
cTAKES, automated annotations:
Sign/symptom type class
 1. Indeterminate fluid collection in the left lower quadrant.
 2. 9 and 5 mm pulmonary nodules at the left lung base, now better visualized due to improving atelectasis. Recommend 3 month follow-up.
Disease/disorder type class
 1. Indeterminate fluid collection in the left lower quadrant.
 2. 9 and 5 mm pulmonary nodules at the left lung base, now better visualized due to improving atelectasis. Recommend 3 month follow-up.