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. 2018 Mar 20;5(1):e000192. doi: 10.1136/bmjgast-2017-000192

Table 4.

Cox proportional hazards model for mortality for patients with HCC

Characteristics Univariable analysis Multivariable analysis
HR (95% CI) P value HR (95% CI) P value
Age, years 1.03 (1.01 to 1.05) 0.04 1.05 (1.01 to 1.09) 0.04
Male 1.05 (0.65 to 1.71) 0.84 0.82 (0.43 to 1.55) 0.54
Ethnicity
 Caucasian 1 (Referent) 1 (Referent)
 Latino/Hispanic 0.51 (0.30 to 0.86) 0.01 0.83 (0.42 to 1.60) 0.57
 Asian 0.52 (0.28 to 0.96) 0.04 0.48 (0.21 to 1.10) 0.08
 African-American 1.62 (0.65 to 4.05) 0.31 1.11 (0.37 to 3.35) 0.86
 Other/Unknown 0.91 (0.33 to 2.54) 0.86 1.15 (0.26 to 5.05) 0.86
Decompensation 1.03 (0.68 to 1.55) 0.90 0.99 (0.54 to 1.84) 0.98
CPT score 1.02 (0.91 to 1.15) 0.73 1.08 (0.93 to 1.25) 0.33
Surveillance
 >q12 months or none* 1 (Referent) 1 (Referent)
 q6–12 months† 1.20 (0.70 to 2.06) 0.50 1.11 (0.49 to 2.49) 0.81
 q6 months‡ 0.32 (0.19 to 0.52) < 0.0001 0.34 (0.16 to 0.72) 0.005
Curative HCC treatment 0.23 (0.14 to 0.40) <0.0001 0.32 (0.17 to 0.61) 0.001
Within Milan criteria 0.52 (0.34 to 0.79) 0.002 0.69 (0.40 to 1.18) 0.17

*Less often than every 12 months or none.

†Less often than every 6 months but more often than every 12 months.

‡At least every 6 months.

CPT, Child-Pugh-Turcotte; HCC, hepatocellular carcinoma.