Table 3.

Ionic concentrations (mM) from inorganic salts in MCDB 131 (non-commercial analog of EGM^™-2), mTeSR^®1, and r-SBF in comparison with human blood plasma. Compiled from Refs. [45,47,51,70].

	MCDB 131	mTeSR®1	r-SBF	Plasma
Na+	124.5	113.74	142	142
K+	4	3.26	5	5
Mg2+	10	0.56	1.5	1.5
Li2+	–	0.98	–	–
Ca2+	1.6	0.82	2.5	2.5
Fe3+	0.001	–	–	–
Cl−	117.2	100.96	103	103
${\text{HCO}}_3^{-}$	14	18	27	27
${\mathrm{H}}_2{\text{PO}}_4^{-}$	0.5	0.36	–	–
${\text{HPO}}_4^{2-}$	–	0.39	1	1
${\text{SO}}_4^{2-}$	10	0.32	0.5	0.5
Ionic Strength	0.173	0.123	0.150	0.150
Osmolality (mOsm/kg H2O)a	260–290b	330–350c		290

^aOsmolality values reported with the presence of organic species and buffers.

^bOsmolality for EGM^™-2 media from technical specification sheet. Lonza Cat# CC-3162.

^cOsmolality for mTeSR^®1 media from technical specification sheet. Stem Cell Tech, Cat# 85850.