Table 3. A KEGG pathway analysis of genes predicted to affect host colonization revealed that the LPS synthesis pathway is significant in determining bacterial abundance in the fly gut.

KO	Pathway	Top Hits	All	p-value	fdr
ko00540	Lipopolysaccharide biosynthesis	9	24	0.0005	0.05
ko00270	Cysteine and methionine metabolism	7	44	0.0350	0.89
ko00480	Glutathione metabolism	4	16	0.0355	0.89
ko01501	beta-Lactam resistance	4	21	0.0600	0.89
ko03020	RNA polymerase	2	5	0.0645	0.89
ko00240	Pyrimidine metabolism	8	61	0.0725	0.89
ko00450	Selenocompound metabolism	3	14	0.0780	0.89

The top hits from the MGWA were grouped into functional pathways and compared by chi-square test to the number of all genes in that pathway from the study. The returned p-value and fdr corrected p-value are listed.