Table 3.
Outcomes at baseline and follow-up, change scores, and treatment effects. Mean (SD) and change are calculated from observed data. Effect estimates (beta) are pooled adjusted coefficients for treatment (internet-based cognitive behavioral therapy, iCBT) versus control (treatment as usual) on follow-up outcomes adjusted for sex, age, and baseline levels of the respective outcomes after multiple imputation.
| Outcome | Baseline, mean (SD) | Follow-up, mean (SD) | Change | Effect, Beta (95% CI) | P value | |
| HADS-Ta | −.47 (−1.95 to 1.00) | .53 | ||||
| iCBT | 18.3 (4.9) | 12.8 (5.9) | −5.5 | |||
| Control | 18.6 (5.0) | 13.6 (6.8) | −5.0 | |||
| HADS-Ab | −.09 (−0.91 to 0.72) | .82 | ||||
| iCBT | 10.9 (2.4) | 7.4 (3.2) | −3.5 | |||
| Control | 10.8 (2.5) | 7.3 (3.7) | −3.5 | |||
| HADS-Dc | −.45 (−1.34 to 0.44) | .32 | ||||
| iCBT | 9.9 (2.2) | 6.6 (3.3) | −3.3 | |||
| Control | 10.3 (2.5) | 8.0 (3.8) | −2.3 | |||
| MADRS-Sd | −.58 (−2.20 to 1.04) | .48 | ||||
| iCBT | 14.8 (6.4) | 12.0 (7.2) | −2.8 | |||
| Control | 15.9 (7.2) | 13.3 (7.6) | −2.6 | |||
| CAQe | −.73 (−2.83 to 1.38) | .50 | ||||
| iCBT | 26.1 (10.3) | 21.5 (10.2) | −5.4 | |||
| Control | 25.3 (10.8) | 22.0 (11.4) | −3.3 | |||
| BADS-SFf | −.50 (−2.31 to 1.30) | .58 | ||||
| iCBT | 21.2 (6.1) | 21.4 (6.9) | 0.2 | |||
| Control | 21.4 (7.7) | 21.6 (7.2) | 0.2 | |||
aHADS-T: Hospital Anxiety and Depression Scale total score.
bHADS-A: Hospital Anxiety and Depression Scale anxiety subscale.
cHADS-D: Hospital Anxiety and Depression Scale depression subscale.
dMADRS-S: The Montgomery-Asberg Depression Rating Scale-Self Rated.
eCAQ: Cardiac Anxiety Questionnaire.
fBADS-SF: Behavioral Activation for Depression Scale-Short Form.