Table 4. Baseline demographics and clinical characteristics based on urinary klotho-to-creatinine ratio.
| Values (N = 65) | rho | P-value | |
|---|---|---|---|
| Log UKCR, pg/mgCr | 4.15 ± 1.67 | – | – |
| Age, years | 35.6 (19.9–48.5) | -0.051 | 0.685 |
| Sex, male | 39 (58.2) | – | 0.056a |
| Hypertension, present | 18 (26.9) | – | 0.799a |
| Diabetes, present | 3 (4.5) | – | 0.020a |
| BMI | 23.6 ± 3.9 | 0.107 | 0.394 |
| Albumin, g/dl | 3.88 ± 0.99 | 0.134 | 0.286 |
| Urea nitrogen, mg/dl | 14.5 (11.2–19.6) | -0.155 | 0.217 |
| Creatinine, mg/dl | 0.8 (0.7–1.0) | -0.150 | 0.233 |
| Calcium, mg/dl | 8.64 ± 0.68 | 0.090 | 0.475 |
| Phosphorus, mg/dl | 3.86 ± 0.82 | 0.093 | 0.460 |
| Total cholesterol, mg/dl | 203.0 (155.5–273.5) | -0.127 | 0.312 |
| Triglycerides, mg/dl | 141.0 (98.5–192.5) | 0.002 | 0.986 |
| eGFR, ml/min per 1.73 m2 | 109.4 (79.8–130.3) | 0.273 | 0.028 |
| UPCR, mg/gCr | 545.4 (193.5–2032.0) | -0.232 | 0.063 |
Data are presented as mean ± SD, median (interquartile range), or count (%) as appropriate. Pearson correlation coefficient or Spearman’s rank correlation coefficients with P-values are presented for the continuous variables.
aP-values of Mann–Whitney U test are presented for the categorical variables. UKCR: urinary klotho-to-creatinine ratio; BMI: body mass index; eGFR: estimated glomerular filtration rate; UPCR: urinary protein-to-creatinine ratio.