Table 5.

Outcome Prediction Results Using Generalized Estimating Equations

	Beta / Exp(B)
	Smoke - Food	Smoke	Food
DMN	−0.766/0.47**	−0.102/0.72	0.678/1.97**
RxGrp	−0.450/0.64**	−0.467/0.63**	0.160/1.17**
Gender	0.137/1.15	0.059/1.06	−0.003/1.00
Age	−0.001/1.00	−0.002/1.00	−0.003/1.00
FTND	0.086/1.09^	0.085/1.09*	0.066/1.07
Scr	0.001/1.00**	0.001/1.00**	0.001/1.00**
Quit	−0.025/0.98*	−0.027/0.97*	−0.027/0.97*
AUDIT	0.013/1.01	0.015/1.02	0.012/1.01
BAI	0.000/1.00	0.001/1.00	0.007/1.01
BDI	0.017/1.02	0.023/1.02	0.013/1.01
BIQ	0.009/1.01	0.027/1.03	0.005/1.01
WSW	−0.024/0.98	−0.019/0.98	−0.018/0.98
WSWFood	−0.005/1.00	0.007/1.01	−0.005/1.00
QSU	0.003/1.003	0.002/1.00	0.003/1.00
rmsRot	−1.126/0.32^	−1.150/0.317^	−1.099/0.33^

^{^}p<0.1

^*Significant at p < 0.05

^**Significant at p < 0.01

Because the interaction terms (Smoke-Food × RxGrp, Smoke × RxGrp, Food × RxGrp) were not significant or trending towards significant, results without the interaction terms are presented. Exp(B) = exponential beta, DMN = default mode network, Smoke - Food = beta for degree of association of DMN component with smoke cues minus for food cues, Smoke = beta for degree of association of DMN component with smoke cues, Food = beta for degree of association of DMN component with food cues, RxGrp = Medication Condition (varenicline = 1, placebo = 0), Gender (male = 1, female = 2), FTND = Fagerstrom Test for Nicotine Dependence, Scr = number of cigarettes smoked during prior 60 days at screen, Quit = Number Serious Quit Attempts (>12 hours abstinent),,AUDIT = AUDIT Total Score, BAI = Beck Anxiety Inventory Total Score, BDI = Beck Depression Inventory Total Score, BIQ = Barratt Impulsiveness Questionnaire Total Score, WSW = Wisconsin Withdrawal Scale Score pre MRI scan, WSWFood=sum of food-related questions only on WSWS, QSU = Questionnaire of Smoking Urges, rmsRot = root mean square translational framewise displacement (head motion at time of MRI scan).