Table 1. Characteristics of ECMO and ECCO2R.
| Characteristic | ECMO | ECCO2R |
|---|---|---|
| Circuit/bypass | Veno-venous bypass | Veno-venous bypass or arterio-venous bypass |
| Blood drainage | From central vein (IJ, FV, SV) | From central vein (IJ, FV, SV) or FA in AV configuration into central vein (IJ, FV, SV) |
| Cannula dimension | 16–31Fr | 8–29Fr |
| Cannula type | Two single cannulas or dual-lumen cannula | Two single cannulas or dual-lumen cannula |
| Pump | Centrifugal | Centrifugal or peristaltic |
| EC blood flow | 2.0–7.0 L/min | 0.2–2.0 L/min |
| CO2 clearance | 100% VCO2, dependent mainly on sweep-gas flow dependent mainly on EC blood flow | 10%–100% VCO2, dependent mainly on sweep-gas flow |
| Oxygen deliver | Not significant | |
| Anticoagulation target | ACT 1.5–2.0 times normal | ACT 1.5 times normal |
| aPTT 1.2–1.8 times normal | aPTT 1.5 times normal |
ECMO: extracorporeal membrane oxygenation; ECCO2R: extracorporeal carbon dioxide removal; IJ: internal jugular vein; FV: femoral vein; SV: subclavian vein; VCO2: carbon dioxide production; EC: extracorporeal; ACT: activated clotting time; aPTT: activated partial thromboplastin time.