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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Hippocampus. 2018 Feb 12;28(4):251–268. doi: 10.1002/hipo.22832

Figure 5.

Figure 5

Select age-related and oxidative function genes were reversed by MCS in ~11 MO trisomic mice. A. Crh is upregulated 1.74 fold (2N versus Ts) in Ts65Dn mice and downregulated in Ts+ mice (Ts+ versus Ts) to 2N levels by MCS. B. Kcnb1 is downregulated 2.19 fold (2N versus Ts) in Ts65Dn mice and upregulated in Ts+ mice (Ts+ versus Ts) to 2N levels by MCS. C. Kcnip3 is downregulated 2.62 fold (2N versus Ts) in Ts65Dn mice and upregulated in Ts+ mice (Ts+ versus Ts) to 2N levels by MCS. D. Mlh1 is upregulated 1.32 fold (2N versus Ts) in Ts65Dn mice and downregulated in Ts+ mice (Ts+ versus Ts) to 2N levels by MCS. Key: **, p<0.005; ***, p<0.001. Upward arrowhead, significant upregulation; downward arrowhead, significant downregulation.