Table 4. The Proportions of HbA1c ≥5.7%, ≥6.1%, and ≥6.5% (%) According to the Quartile of WBC Level.
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P value | |
|---|---|---|---|---|---|
| WBC counts, /µL | 4,000–4,990 | 4,991–5,790 | 5,791–6,780 | 6,781–10,000 | |
| Number | 1,795 | 1,765 | 1,777 | 1,779 | |
| HbA1c (≥5.7%), % | |||||
| Model 1a | 29.7 | 33.6 | 36.9 | 40.6 | <0.001 |
| Model 2b | 29.7±1.0 | 33.4±1.0 | 37.0±1.0 | 40.7±1.0 | <0.001 |
| Model 3c | 30.9±1.0 | 34.1±1.0 | 36.6±1.0 | 39.3±1.0 | <0.001 |
| Model 4d | 29.0±1.0 | 32.1±1.0 | 34.8±1.0 | 37.9±1.0 | <0.001 |
| HbA1c (≥6.1%), % | |||||
| Model 1a | 6.9 | 9.1 | 10.5 | 12.4 | <0.001 |
| Model 2b | 7.6±0.6 | 9.3±0.6 | 10.3±0.6 | 11.6±0.6 | <0.001 |
| Model 3c | 7.9±0.6 | 9.4±0.6 | 10.3±0.6 | 11.2±0.6 | 0.002 |
| Model 4d | 5.7±0.6 | 7.1±0.6 | 8.0±0.6 | 8.9±0.6 | 0.001 |
| HbA1c (≥6.5%), % | |||||
| Model 1a | 2.1 | 2.6 | 4.3 | 5.2 | <0.001 |
| Model 2b | 3.1±0.4 | 2.9±0.4 | 4.1±0.3 | 4.2±0.4 | 0.014 |
| Model 3c | 3.1±0.4 | 2.9±0.4 | 4.1±0.4 | 4.1±0.4 | 0.022 |
| Model 4d | 1.1±0.3 | 1.2±0.3 | 1.9±0.3 | 2.0±0.3 | 0.045 |
Values are expressed as mean±SEM.
HbA1c, hemoglobin A1c; WBC, white blood cell.
aModel 1: unadjusted; bModel 2: adjusted for age, sex, and fasting plasma glucose (FPG); cModel 3: adjusted for college graduation, smoking history (never, past, and current smoking), waist circumference, the presence of hypertension, serum total cholesterol, serum triglyceride, the presence of anemia, and variables in model 2; dModel 4, model 3 after exclusion of FPG ≥126 mg/dL (n=204).