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. 2018 Mar 29;7:45. doi: 10.1038/s41426-018-0048-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a The mapping depths of 19 adhesion and biofilm formation genes were detected in all ST188 isolates of this study. A gene with a two-fold higher mapping depth than the average genome sequencing depth was determined as a gene with multiple (≥2) copies (dark blue splits). Genes with one copy were indicated by light blue splits, and genes represented by white splits were determined as absent. b, c Quantitative RT-PCR analysis of genes with multiple (≥2) copies in host-adapted S. aureus ST188 compared with that of host-adapted S. aureus ST398 (10 isolates were randomly selected/lineage). *, P < 0.05; **, P < 0.01; NS, not significant (P ≥ 0.05)