Table 4. Distribution of HPV subtypes in cervical cancer tissues of different histopathology based on age group.
| HPV types | Percentage of HPV infection (%)* | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 20–39 years (N=23) | 40–59 years (N=103) | 60–79 years (N=29) | |||||||
| SCC† (N=14) | ADC† (N=8) | Other (N=1) | SCC† (N=67) | ADC† (N=28) | Other (N=8) | SCC† (N=20) | ADC† (N=7) | Other (N=2) | |
| HPV16 | 42.9 | 37.5 | – | 40.3 | 42.9 | 12.5 | 25.0 | 28.6 | – |
| HPV18 | 21.4 | 50.0 | 100.0 | 20.9 | 25.0 | 50.0 | 25.0 | 14.3 | 50.0 |
| HPV31 | – | – | – | 1.5 | 7.1 | – | – | – | – |
| HPV33 | 14.3 | – | – | 11.9 | 3.6 | – | – | – | – |
| HPV35 | – | – | – | 1.5 | – | – | – | – | – |
| HPV45 | –- | – | – | 1.5 | 3.6 | 12.5 | – | – | – |
| HPV52 | –- | – | – | – | – | – | 5.0 | 14.3 | – |
| HPV53 | – | – | – | – | – | – | 10.0 | – | – |
| HPV58 | 7.1 | 12.5 | – | 10.4 | 3.6 | 25.0 | 5.0 | 14.3 | – |
| HPV66/68‡ | 7.1 | – | – | 3.0 | – | – | 5.0 | – | – |
| HPV73 | – | – | – | – | – | – | 5.0 | – | – |
| HPV81 | – | – | – | – | 7.1 | – | 5.0 | 14.3 | – |
| HPV82 | – | – | – | – | – | – | – | – | 50.0 |
| HPV16 + 18 | – | – | – | 6.0 | 3.6 | – | 10.0 | 14.3 | – |
| HPV16 + 81 | – | – | – | 1.5 | – | – | – | – | – |
| HPV16 + 84/26‡ | 7.1 | – | – | – | – | – | – | – | – |
| HPV18 + 52 | – | – | – | – | 3.6 | – | – | – | – |
| HPV18 + 58 | – | – | – | – | – | – | 5.0 | – | – |
| HPV31 + 45 | – | – | – | 1.5 | – | – | – | – | – |
*
Total percentage may not be equal to 100.0% due to rounding.
†
Abbreviations: ADC, adenocarcinoma; SCC, squamous cell carcinoma.
‡
The HPV genotyping kit used could not distinguish between HPV66 and HPV68, and between HPV84 and HPV26.