Table 3.
Allele and genotype frequencies of IL-10 in total cerebral palsy (CP) patients and controls.
| Group | Allele frequency | p Value | p΄ Value | OR (95% CI) | Genotype frequency | p Value | H–W | |||
|---|---|---|---|---|---|---|---|---|---|---|
| rs1554286 | C | T | C/C | C/T | T/T | |||||
| CP | 181 (0.322) | 381 (0.678) | 0.023 | 0.731 [0.558–0.958] | 29 (0.103) | 123 (0.438) | 129 (0.459) | 0.032 | 0.968 | |
| Control | 152 (0.394) | 234 (0.606) | 36 (0.187) | 80 (0.415) | 77 (0.399) | 0.067 | ||||
| rs1518111 | A | G | A/A | A/G | G/G | |||||
| CP | 388 (0.690) | 174 (0.310) | 0.018 | 1.387 [1.056–1.820] | 132 (0.470) | 124 (0.441) | 25 (0.089) | 0.017 | 0.589 | |
| Control | 238 (0.617) | 148 (0.383) | 79 (0.409) | 80 (0.415) | 34 (0.176) | 0.087 | ||||
| rs3024490 | G | T | G/G | G/T | T/T | |||||
| CP | 170 (0.306) | 386 (0.694) | 0.011 | 0.033 | 0.702 [0.533–0.924] | 24 (0.086) | 122 (0.439) | 132 (0.475) | 0.018 | 0.574 |
| Control | 145 (0.386) | 231 (0.614) | 32 (0.170) | 81 (0.431) | 75 (0.399) | 0.214 | ||||
| rs1800871 | C | T | C/C | C/T | T/T | |||||
| CP | 162 (0.307) | 366 (0.693) | 0.011 | 0.033 | 0.696 [0.527–0.921] | 25 (0.095) | 112 (0.424) | 127 (0.481) | 0.018 | 0.966 |
| Control | 143 (0.389) | 255 (0.611) | 34 (0.185) | 75 (0.408) | 75 (0.408) | 0.054 | ||||
| rs1800896 | A | G | A/A | A/G | G/G | |||||
| CP | 525 (0.934) | 37 (0.066) | 0.019 | 1.732 [1.091–2.751] | 246 (0.875) | 33 (0.117) | 2 (0.007) | 0.053 | 0.448 | |
| Control | 344 (0.891) | 42 (0.109) | 153 (0.793) | 38 (0.197) | 2 (0.010) | 0.832 | ||||
p′-Value, the p-value after the SNPSpD correction; The significance was set at p′<0.05 after correction; OR, odds ratio; CI, confidence interval.