Table 5.
Allele and genotype frequencies of IL-10 in cerebral palsy (CP) patient subgroups and controls.
| Group | Allele frequency | p-Value | p΄-Value | OR [95% CI] | Genotype frequency | p-Value | p΄-Value | H–W | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| rs1554286 | C | T | C/C | C/T | T/T | ||||||
| CP + tetraplegia | 70 (0.285) | 176 (0.715) | 0.005 | 0.015 | 0.612 [0.434–0.864] | 9 (0.073) | 52 (0.423) | 62 (0.504) | 0.013 | 0.039 | 0.671 |
| Control | 152 (0.394) | 234 (0.606) | 36 (0.187) | 80 (0.415) | 77 (0.399) | 0.067 | |||||
| rs1518111 | A | G | A/A | A/G | G/G | ||||||
| CP + tetraplegia | 180 (0.732) | 66 (0.268) | 0.003 | 0.009 | 1.696 [1.197–2.404] | 64 (0.520) | 52 (0.423) | 7 (0.057) | 0.006 | 0.018 | 0.395 |
| Control | 238 (0.617) | 148 (0.383) | 79 (0.409) | 80 (0.415) | 34 (0.176) | 0.087 | |||||
| rs3024490 | G | T | G/G | G/T | T/T | ||||||
| CP + tetraplegia | 64 (0.264) | 178 (0.736) | 0.002 | 0.006 | 0.573 [0.402–0.815] | 7 (0.058) | 50 (0.413) | 64 (0.529) | 0.009 | 0.027 | 0.494 |
| Control | 145 (0.386) | 231 (0.614) | 32 (0.170) | 81 (0.431) | 75 (0.399) | 0.214 | |||||
| rs1800871 | C | T | C/C | C/T | T/T | ||||||
| CP + tetraplegia | 60 (0.259) | 172 (0.741) | 0.001 | 0.003 | 0.549 [0.383–0.787] | 7 (0.060) | 46 (0.397) | 63 (0.543) | 0.004 | 0.012 | 0.713 |
| Control | 143 (0.389) | 255 (0.611) | 34 (0.185) | 75 (0.408) | 75 (0.408) | 0.054 | |||||
| rs1800896 | A | G | A/A | A/G | G/G | ||||||
| CP + tetraplegia | 236 (0.959) | 10 (0.041) | 0.002 | 0.006 | 2.881 [1.418–5.856] | 113 (0.919) | 10 (0.081) | 0 (0.000) | 0.010 | 0.030 | 0.638 |
| Control | 344 (0.891) | 42 (0.109) | 153 (0.793) | 38 (0.197) | 2 (0.010) | 0.832 | |||||
p΄-Value, the p-value after the SNPSpD correction; The significance was set at p΄<0.05 after correction; OR, odds ratio; CI, confidence interval.