Table 2.

One - year changes in biochemical parameters according to study subgroups

	Biochemical parameter	Pre-treatment	Post-treatment	p–value
Omeprazole group (n=42)	Homocysteine	14.3±3.9	14.5±3.0	0.48
	Vitamin B12	404.9±111.7	381.6±122.9	0.02
	Ferritin	133.1±101.1	99.5±87.9	0.01
	Iron	17.6±5.7	16.2±6.1	0.13
Esomeprazole group (n=41)	Homocysteine	14.1±3.0	14.5±2.3	0.19
	Vitamin B12	439.4±128.4	395.6±156.6	0.02
	Ferritin	121.0±105.5	91.2±67.8	0.001
	Iron	17.8±4.4	17.4±4.3	0.29
Lansoprazole group (n=42)	Homocysteine	14.9±3.4	15.1±2.7	0.79
	Vitamin B12	438.2±127.3	396.6±143.7	0.004
	Ferritin	138.7±114.7	93.3±76.7	0.001
	Iron	18.2±6.3	17.6±5.9	0.64
Pantoprazole group (n=42)	Homocysteine	13.5±2.6	13.9±7.2	0.81
	Vitamin B12	452.1±121.4	399.9±137.2	0.01
	Ferritin	147.6±124.3	92.4±73.4	<0.001
	Iron	16.9±4.6	16.8±5.2	0.30
Control group (n=42)	Homocysteine	14.7±4.3	13.8±3.2	0.08
	Vitamin B12	418.9±127.3	416.2±115.6	0.66
	Ferritin	105.8±87.4	87.6±82.8	0.21
	Iron	19.0±4.9	19.6±4.9	0.15

p-values according to Wilcoxon signed-rank test; All the parameters are expressed as mean± standard deviation;