Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

letter

. 2018 Mar 29;5:18008. doi: 10.1038/hgv.2018.8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Graphical view of iMETHYL. (a) Three-layer omics data are provided as browser tracks. The browser displays several tracks, which are shown for the region surrounding the DNAm biomarker for tobacco smoking, cg05575921. Users can select tracks that provide information from external sources on gene structure, expression, and SNVs and cell-type-specific original tracks (e.g., CD4T, monocytes, and neutrophils) that show average DNAm levels and different measures of variation (SD and RI). (b–d) Detailed information on CpG tracks for CD4T, monocytes, and neutrophils. The frequencies of the three DNAm categories among individuals are shown as Mlf_high (≥ 67%), Mlf_mid (34–66%), and Mlf_low (≤ 33%). CD4T, CD4+ T-lymphocytes; DNAm, DNA methylation; Mlf_high, frequency of hypermethylated DNA; Mlf_high, frequency of hypermethylated DNA; Mlf_low, frequency of hypomethylated DNA; Mlf_mid, frequency of intermediate methylation DNA; RI, reference interval; SD, standard deviation; SNV, single-nucleotide variation.