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. 2018 Mar 29;5:18008. doi: 10.1038/hgv.2018.8

Table 1. Demographic and profile statistics of iMETHYL.

  Monocytes CD4+ T cells Neutrophils
Demographic characteristics of subjects
 N 102a 102a 94
 Males, N (%) 48 (47.1) 49 (48.0) 48 (51.1)
 Median age (range), years 62.5 (35–75) 62.0 (35–75) 58.0 (24–81)
       
DNAm profiles
 Sequencing depthb 31.1±1.8 31.0±1.6 54.7±1.6
 No. of autosomal CpGsc 23 ,941,821 24,037,518 25,483,031
       
Gene expression profiles
 No. of sequencing readsb 33,917,157±3,153,528 35,175,996±1,275,575 47,040,140±6,289,540
 No. of genesd 16,282 18,299 14,534
       
SNV profiles
 Sequencing depthb 27.2±1.0 27.2±1.0 53.3±13.2
 No. of SNVse 8,945,669 8,951,822 8,792,880

Abbreviations: DNAm, DNA methylation; SNV, single-nucleotide variant.

a

Both cell types were obtained from the same 95 individuals out of a cohort of 102.

b

Average±standard deviation.

c

CpGs that were retained in ≥50% of subjects for each cell type.

d

Genes that were expressed with a fragments per kilobase of exon per million mapped fragments ≥0.1 in ≥50% of subjects for each cell type.

e

SNVs with a minor allele count >1.