Table 1. Demographic and profile statistics of iMETHYL.
Monocytes | CD4+ T cells | Neutrophils | |
---|---|---|---|
Demographic characteristics of subjects | |||
N | 102a | 102a | 94 |
Males, N (%) | 48 (47.1) | 49 (48.0) | 48 (51.1) |
Median age (range), years | 62.5 (35–75) | 62.0 (35–75) | 58.0 (24–81) |
DNAm profiles | |||
Sequencing depthb | 31.1±1.8 | 31.0±1.6 | 54.7±1.6 |
No. of autosomal CpGsc | 23 ,941,821 | 24,037,518 | 25,483,031 |
Gene expression profiles | |||
No. of sequencing readsb | 33,917,157±3,153,528 | 35,175,996±1,275,575 | 47,040,140±6,289,540 |
No. of genesd | 16,282 | 18,299 | 14,534 |
SNV profiles | |||
Sequencing depthb | 27.2±1.0 | 27.2±1.0 | 53.3±13.2 |
No. of SNVse | 8,945,669 | 8,951,822 | 8,792,880 |
Abbreviations: DNAm, DNA methylation; SNV, single-nucleotide variant.
Both cell types were obtained from the same 95 individuals out of a cohort of 102.
Average±standard deviation.
CpGs that were retained in ≥50% of subjects for each cell type.
Genes that were expressed with a fragments per kilobase of exon per million mapped fragments ≥0.1 in ≥50% of subjects for each cell type.
SNVs with a minor allele count >1.