FIG 3.

A majority of miRNA target sites are located within the CDS. The transcript region from which each hybrid mRNA fragment originated was determined. The regions were categorized as 5′ UTR, 5′ UTR-CDS, CDS, CDS-3′ UTR, or 3′ UTR. Hybrid mRNAs for which the transcript was not annotated in the database were omitted. (A) Comparison of transcript regions from wild-type-infected (WT), ΔmiR-K12-11-infected (Δ11), and uninfected (UI) TIVE-EX-LTC cells. (B) Comparison of hybrids containing KSHV miRNAs from either WT- or ΔmiR-K12-11-infected cells against hybrids containing cellular miRNAs from WT-infected cells, ΔmiR-K12-11-infected cells, and uninfected cells. The total number of hybrids is indicated above each bar.