FIG 9.
B cell hybrids have unique characteristics. Spontaneously occurring hybrids in B cells from previously reported CLIP data were analyzed in the same manner as for hybrids identified by qCLASH in TIVE-EX-LTC cells. (A and B) Comparisons of mRNA regions of origin in viral and cellular hybrids from BCBL-1 cells with those of BC-3 cell hybrids (A) and hybrids containing KSHV miRNAs from either BCBL-1 or BC-3 cells with hybrids containing cellular miRNAs from either cell type (B). Hybrid mRNAs for which the transcript was not annotated in the database are omitted. (C to E) Comparisons of seed pairing types in viral and cellular hybrids from BCBL-1 cells with those from BC-3 cell hybrids (C), hybrids containing KSHV miRNAs from either BCBL-1 or BC-3 cells with hybrids containing cellular miRNAs from either cell type (D), and all hybrids in both BCBL-1 and BC-3 cells (viral and cellular) with the miRNA at the 5′ end with all hybrids with the miRNA at the 3′ end (E).