FIG 6.

B.1059 immunization increases the frequency and magnitude of plasma IgA responses. Plasma IgA responses against HIV-1 envelope antigens were examined by the BAMA. Plasma after two NYVAC and five protein immunizations was tested at a 1:40 dilution. Values greater than 100 and 3-fold over baseline were considered positive responses. Nonresponders are represented by open symbols. The box-and-whisker plots show the median, interquartile range, minimum, and maximum. No detectable binding was measured for antigens A1.con.env03 gp140CF, CON-S gp140CFI, SF162.LS gp140C, and 00MSA 4076 gp140.