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. 2018 Mar 22;9:526. doi: 10.3389/fmicb.2018.00526

FIGURE 5.

FIGURE 5

Analysis of viral pathogenesis in vivo. Groups of 10 female C57BL/6J mice (10–12 weeks of age) were infected intra-nasally with 5 × 105 FFU of Gi-wt or Gi-NS-PR8 virus. (A) Calculated percentages of body weight loss was recorded up to 14 days p.i.. Differences in weight loss between infection with Gi-wt and with Gi-NS-PR8 were significant (p < 0.025, repeated measures ANOVA) for days 1–4. Error bars indicate means ± SEM. (B) Percentages of mice surviving at the indicated time points (up to 14 days p.i.). Mice had to be euthanized when weight loss exceeded 20%. Asterisk (∗) refers to significant difference of means.