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. 2018 Mar 21;13:53–63. doi: 10.1515/med-2018-0010

Table 2.

Comparison of the efficacy and safety of treatment in the three groups

Variable A group (n = 73) B group (n = 71) C group (n = 72) X2 P
Therapeutic efficacy n (%) abc
Complete normalization individual quantity 61(83.6%) 47(66.2%) 44(61.1%)
Partial improvement individual quantity 4(5.5%) 7(9.9%) 8(11.1%) 9.612 0.008
No improvement individual quantity 8(10.9%) 17(23.9%) 20(27.8%)
Safety n (%) with adverse reactions
Mild 5(6.85%) 6(8.45%) 5(6.94%) 0.168 0.919
Moderate 1(1.4%) 1(1.4%) 1(1.4%) 0.000 1.000
Severe 0(0%) 0(0%) 0(0%)

A group received bicyclol tablets, B group received diammonium glycyrrhizinate enteric–coated capsules, and C group received silibinin capsules.

Statistical significance of differences between groups in therapeutic efficacy:

a : A vs B, significant (P = 0.016).

b: A vs C, very significant (P = 0.003).

c: B vs C, not statistically significant (P = 0.531).