Table 2.
The table reports passive and active parameters of fresh and frozen cortical neurons.
| Parameters | Fresh | 2 weeks | 4 weeks |
|---|---|---|---|
| Resting membrane potential (mV) | −56.5 ± 2.4 | −59.5 ± 1.4 | −57.1 ± 2.5 |
| Cell membrane capacitance (pF) | 63.2 ± 6.2 | 80.3 ± 7.9 | 79.8 ± 5.8 |
| Input resistance (MΩ) | 119 ± 23 | 106 ± 14 | 163 ± 31 |
| Maximal firing frequency (Hz) | 68.1 ± 9.4 | 60.3 ± 8.2 | 64.9 ± 13.1 |
| AP threshold (mV) | −26.5 ± 1.6 | −30.3 ± 1.4 | −33.7 ± 2.1 |
| AP amplitude (mV) | 54.3 ± 1.9 | 50.0 ± 3.3 | 56.6 ± 1.5 |
| Half-width (ms) | 1.3 ± 0.1 | 1.4 ± 0.3 | 1.3 ± 0.2 |
| AHP amplitude (mV) | 11.6 ± 0.9 | 11.9 ± 1.1 | 11.8 ± 0.8 |
| Overshoot (mV) | 27.7 ± 2.4 | 19.8 ± 3.5 | 22.5 ± 3.1 |
| Peak Na current (pA/pF) | −79.8 ± 7.5 | −62.0 ± 14.2 | −95.3 ± 17.1 |
| Peak K current (pA/pF) | 116.7 ± 14.0 | 68.9 ± 17.8 | 111.1 ± 18.9 |
Value are expressed as mean ± SEM, n = 7–11; AP, action potential; AHP, after hyper-polarization.