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. 2018 Mar 22;9:259. doi: 10.3389/fphys.2018.00259

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Copyright © 2018 Messina, Monda, Valenzano, Messina, Villano, Moscatelli, Cibelli, Marsala, Polito, Ruberto, Carotenuto, Monda, Viggiano, Daniele and Nigro.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Means ± SD of values of T_c. Intracerebroventricular (icv) injection of adiponectin (0.1 μg/g), or saline or orexin A (1.5 nmol) was made at time 0 and they were monitored each 30 for 180 min. post-injections. ^***p < 0.001; ^*p < 0.05.