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. 2017 Dec 25;6(1):1. doi: 10.3390/vaccines6010001

Table 1.

Predicted antigenic epitopes within the MIC-A protein. A total of 14 epitopes are predicted, with six of those found within the transmembrane topology depicting potential antigenic peptides. More so, seven of the predicted epitopes are located outside the transmembrane topology and another one is found on the transmembrane itself; these are non-antigenic in nature.

S/N Sequence Start Position End Position TMHMM TMHMM Score
1 GPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWGSVQSGFL
TEVHLDGQPFLRCDRQKCRA
4 66 Outside 0.04288
2 RMTLAHI 97 103 Inside 0.66097
3 EGLHSLQEIRVCEI 108 121 Outside 0.25679
4 SSQHFYYDGELFLSQ 129 143 Outside 0.21811
5 KTHYHAMHADCLQELRR 177 193 Inside 0.76815
6 LKSGVVLRR 195 203 Inside 0.56129
7 VPPMVNV 205 211 Outside 0.25411
8 ITVTCRASG 221 229 Inside 0.73449
9 DGVSLSH 242 248 Outside 0.17761
10 YQTWVATRICQ 264 274 Inside 0.87917
11 QRFTCYM 278 284 Inside 0.79020
12 STHPVPSGKVLVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKK 291 333 Transmembrane 0.00369
13 EGPELVSLQVLDQHPVGT 339 356 Outside 0.07341
14 TQLGFQPLMS 363 372 Outside 0.17418