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. 2017 Dec 25;6(1):2. doi: 10.3390/vaccines6010002

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Molecular representation of PorB/VDs. Cartoon of predicted trimers (top view) created with Swiss-Model server [63,64] and NGL Viewer 0.9.0 [65] based on the Nme PorB template (PDB ID 3WI4) [66]. Loops are depicted as follows: L1: Red. L2: Orange. L3: Ochre. L4: Yellow. L5: Lime green. L6: Green. L7: Teal. L8: Blue. (A) NL PorB; (B) PorB/VD1: NL PorB L5 (lime green) is replaced with MOMP L2 containing VD1; (C) PorB/VD2: NL PorB L6 (green) is replaced with MOMP L3 containing VD2; (D) PorB/VD3: NL PorB L7 (teal) is replaced with MOMP L5 containing VD3; (E) PorB/VD4: NL PorB L4 (yellow) is replaced with MOMP L6 containing VD4.