Table 2.
Immunization with NL PorB and PorB/VDs induces different cytokine responses.
| Cytokine | PorB/VD1 | PorB/VD2 | PorB/VD3 | PorB/VD4 | NL PorB |
|---|---|---|---|---|---|
| IL-4 a | 1.19 ± 0.55 | 3.56 ± 0.7 | 3.1 ± 0.72 | 2.29 ± 0.09 | 2.57 ± 0.67 |
| IFN-γ a | 5.44 ± 0.2 | 10.05 ± 4.79 | 3.65 ± 0.25 | 2.08 ± 0.62 | 2.84 ± 1.09 |
| Th1:Th2 index ^ | 2.85 | 2.81 | 1.80 | 0.90 | 1.10 |
| IL-6 a | 5.23 ±0.82 | 16.63 ± 3.47 | 7.6 ± 1.12 | 11.14 ± 2.56 | 4.81 ± 1.7 |
| TNF-α a | 7.87 ± 1.78 | 1.58 ± 0.67 | 5.9 ± 0.68 | 12.75 ± 3.63 | 0.46 ± 0.24 |
a Cytokines fold-change measured as immune sera/pre-immune sera (pg/mL ± SEM). ^ Th1:Th2 index measured as IFN-γ (pg/mL)/IL-4 (pg/mL).