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Drawing of the HIV Env trimer and its potential accessibility on VLPs. In the left drawing, Env is depicted with gp120 in light brown and the visible parts of gp41 containing the transmembrane region in dark blue. In the middle drawing, VLPs, scarcely coated with Env, can be seen to be approachable from all angles. Dense coating of the VLPs, as depicted in the right drawing, makes gp120 more accessible relative to gp41.
