Figure 4.

Peptide VI compared to vancomycin in preventing clinical isolate MRSA (M) adhesion and consequent biofilm formation on the implant’s surface made from poly(methyl methacrylate)-based bone cement (Palacos®r). The bone cement contained peptide VI (5 mg), vancomycin (5 mg) or was unloaded as a control. Bacteria infiltrated towards the implants from a hole drilled into bone tissue between them. The bars represent mean value ± SEM at least from three independent measurements. Statistical differences between groups were calculated using one-way ANOVA (* p < 0.05).