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. 2018 Mar 8;11(1):28. doi: 10.3390/ph11010028

Table 2.

Effects of different LMWC concentrations in the aqueous phase during the creation of PLGA NPs loaded with tobramycin based on size (nm), polydispersity index (PDI), charge (mV), drug entrapment efficiency (EE) (percentage), and loading capacity (LC) (percentage).

Formulae Size (nm) PDI Zeta Potential (mV) EE (%) LC (%)
Control 187.00 ± 6.19 0.206 ±0.014 +45.00 ± 4.30 NA NA
F0 220.70 ± 1.77 0.194 ±0.002 −2.80 ± 0.10 85.34% 45.92%
F0.25 309.57 ± 1.12 0.295 ±0.011 +34.00 ± 1.90 88.47% 43.15%
F0.5 451.80 ± 7.19 0.297 ±0.106 +50.13 ± 6.50 87.20% 37.33%
F1 575.77 ± 2.67 0.319 ±0.130 +33.47 ± 1.00 83.74% 30.87%