Table 5.
Plasma cholinesterase activity, serum oxidative stress biomarkers, and genotoxicity parameters in controls and pesticide sprayers.
| Biomarkers | Controls | Pesticide Sprayers | p-Value |
|---|---|---|---|
| PChE (KU/L) | 0.30 ± 0.07 | 0.23 ± 0.10 | <0.001 |
| CAT (U) | 64.11 (32.10–96.63) | 64.12 (49.45–103.92) | 0.185 |
| SOD (U) | 16.81 (14.22–18.10) | 27.91 (15.52–36.63) | <0.001 |
| TBARS (μM) | 0.18 (0.12–0.28) | 0.24(0.13–0.49) | 0.009 |
| GSH (μM) | 81.75 (71.35–97.74) | 42.04 (41.33–43.55) | <0.001 |
| PrC (mM) | 2.20 (1.58–2.97) | 5.45 (2.96–8.14) | <0.001 |
| TAC (mM) | 0.85 (0.73–0.96) | 1.07 (0.87–1.37) | <0.001 |
| Density of 180 bp band (%) | 4.55 ± 0.40 | 4.82 ± 0.43 | <0.001 |
| Density of 360 bp band (%) | 3.96 (3.78–4.28) | 4.22 (4.01–4.64) | <0.001 |
| Density of 540 bp band (%) | 3.50 (3.29–3.75) | 3.70(3.42–4.13) | <0.001 |
| Tail length (pixels) | 3.03 (3.01–3.08) | 3.07 (3.03–3.20) | 0.002 |
| Tail DNA (%) | 1.06 ± 0.29 | 1.60 ± 0.43 | <0.001 |
| Tail moment (AU) | 0.03 (0.03–0.04) | 0.05 (0.04–0.08) | <0.001 |
| Olive Tail moment (AU) | 0.25 (0.21–0.27) | 0.35 (0.31–0.39) | <0.001 |
Data are expressed as median (IQR) or means ± SD and comparisons were made by using the Mann–Whitney U test or Student’s-sample t-test, respectively. The bold p-values represent the significant differences between study groups. PChE: plasma cholinesterase, CAT: catalase, SOD: superoxide dismutase, TBARS: thiobarbituric acid reactive substances, GSH: glutathione, PrC: protein carbonyl, TAC: total antioxidant capacity, AU: arbitrary unit.