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. Author manuscript; available in PMC: 2018 Oct 17.
Published in final edited form as: Acc Chem Res. 2017 Sep 28;50(10):2577–2588. doi: 10.1021/acs.accounts.7b00347

Table 2.

DC50 and rdl Values for (–)-Lomaiviticin A (4)a

entry oligonucleotide duplexes DC50 (per base pair) rdl
1 graphic file with name nihms951574t1.jpg 18.3 ± 1.4 μM 0.09
2 graphic file with name nihms951574t2.jpg
graphic file with name nihms951574t3.jpg
2.70 ± 0.38 μM 0.2
3 graphic file with name nihms951574t4.jpg 2.14 ± 0.18 μM 0.5
4 graphic file with name nihms951574t5.jpg 1.87 ± 0.14 μM 0.5
5 graphic file with name nihms951574t6.jpg 0.85 ± 0.05 μM 1.0
a

For the conditions, see ref 39.