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. 2018 Feb 11;10(1):24. doi: 10.3390/pharmaceutics10010024

Table 2.

Mean ± SD diameter, weight variation (WV), content uniformity (CU), breaking force (BF), friability (F), and drug dissolution (DD) for the taste-masked rapidly-disintegrating sublingual tablet formulations.

Characteristics Formulations
Placebo Epi 30
Diameter (mm) 9.98 ± 0.01 9.98 ± 0.01
WV (mg), (AV) a 202 ± 2.58 (3.1) 211 ± 2.85 (6.47)
CU (%), (AV) a N/A 102 ± 4.77 (10.94)
BF (kgf) 2.53 ± 0.02 2.50 ± 0.01
F (%) 0.1 0.7
DD (%) b N/A 102.97 ± 8.28

a AV, USP acceptance value (values ≤15.00 were considered acceptable according to USP L1 limit); b DD (%), Percentage of drug dissolved in the first 120 s.