TABLE 1 .
Selected upregulated host immunity genesa
| Ensembl ID | Gene name | Product | Log2-fold change (WT versus PBS) |
|---|---|---|---|
| ENSMUSG00000058427 | CXCL2 | Growth-regulated alpha protein 2 | 7.04 |
| ENSMUSG00000038067 | Csf3 | Colony-stimulating factor 3 | 6.98 |
| ENSMUSG00000000982 | Ccl3 | C-C motif chemokine 3 | 6.83 |
| ENSMUSG00000032691 | Nlrp3 | Cryopyrin | 5.86 |
| ENSMUSG00000025746 | IL6 | Interleukin-6 | 5.71 |
| ENSMUSG00000018930 | Ccl4 | C-C motif chemokine 4 | 5.41 |
| ENSMUSG00000042265 | Trem1 | Triggering receptor expressed on myeloid cells 1 | 5.38 |
| ENSMUSG00000029380 | CXCL1 | Growth-regulated alpha protein 2 | 5.28 |
| ENSMUSG00000027398 | II1b | Interleukin-1β | 5.14 |
| ENSMUSG00000027399 | II1a | Interleukin-1α | 5.12 |
| ENSMUSG00000029379 | CXCL3 | Growth-regulated alpha protein 3 | 5.11 |
| ENSMUSG00000078817 | Nlrp12 | Nlrp12 protein | 3.65 |
| ENSMUSG00000024401 | Tnf | Tumor necrosis factor | 3.22 |
| ENSMUSG00000027995 | Tlr2 | Toll-like receptor 2 | 3.06 |
| ENSMUSG00000035385 | Ccl2 | C-C motif chemokine 2 | 3.03 |
| ENSMUSG00000026180 | Cxcr2 | CXC chemokine receptor | 2.39 |
| ENSMUSG00000025225 | NF-κB | Nuclear factor NF-kappa-B | 2.28 |
| ENSMUSG00000035373 | Ccl7 | C-C motif chemokine 7 | 2.24 |
| ENSMUSG00000022534 | Mefv | Pyrin | 2.23 |
a
Upregulation was defined by an FDR value of <0.01 and a log2(fold change) of >2. ID, identifier; WT, wild-type infected mice; PBS, mice treated with phosphate-buffered saline.