Table 4.
Frequency of CYP4F2 rs1558139 genotypes and alleles in the groups of optic neuritis (ON) patients with and without MS by gender.
| Gene | Genotype/allele | Frequency (%) | |||||
|---|---|---|---|---|---|---|---|
| ON without MS group n (%) |
P value | ON with MS group n (%) |
P value | ||||
| Women n = 12 |
Men n = 7 |
Women n = 15 |
Men n = 6 |
||||
|
CYP4F2
rs1558139 |
Genotype | ||||||
| G/G | 3 (27) | 1 (14.3) | 1.000 | 6 (32.1) | 4 (66.7) | 0.362 | |
| G/A | 9 (75) | 2 (28.6) | 0.074 | 5 (53.6) | 2 (33.3) | 1.000 | |
| A/A | 0 (0) | 4 (57.1) | 0.009 | 4 (14.3) | 0 (0) | 0.281 | |
| Total | 12 (100) | 7 (100) | 15 (100) | 6 (100) | |||
| Allele | |||||||
| G | 15 (62.5) | 4 (28.6) | 0.044 | 17 (56.7) | 10 (83.33) | 0.158 | |
| A | 9 (37.5) | 10 (71.4) | 13 (43.3) | 2 (16.67) | |||
ON: optic neuritis; MS: multiple sclerosis: p value: significance level (alpha = 0.05).