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. 2018 Apr;24(4):718–726. doi: 10.3201/eid2404.170141

Figure 4.

Figure 4

Potential lineage of ring-stage Plasmodium falciparum isolates with high survival rates according to ring-stage assay (RSA) in Uganda. Principal component analysis (A) and STRUCTURE (34) analysis (B) suggested an indigenous emergence of parasites with high survival rates by RSA (H2, H3, and H4) in Africa. P. falciparum isolates (n = 31) that originated from Asia (n = 19), including 6 isolates with PfKelch13 mutation, or from Africa (n = 12) were obtained from Sequence Read Archive in National Center for Biotechnology Information (https://www.ncbi.nlm.nih.gov/sra). DRC, Democratic Republic of the Congo; PC1, first principal component; PC2, second principal component; WT, wild-type.