Graphic presentation of normalized mean mRNA levels (±SD) of cell
cycle regulatory genes. Shown are mean mRNA levels of cyclin D1
(A), cyclin A2 (B), cyclin B1
(C), cyclin B2 (D), cyclin F
(E), Cdc25B (F), and p55cdc
(G) at various intervals in regenerating liver (in
triplicate). The regenerating liver was obtained from 2-month-old wt
mice (blue), 12-month-old tg mice (green), or 12-month-old wt mice
(red). Expression levels of cell cycle regulatory genes were normalized
to the GAPDH mRNA levels. The expression level of the 2-month-old
regenerating mouse liver at 24 h after PHx was set at 1.0.