Figure. Treatment Effects of Cholesteryl Ester Transfer Protein (CETP) Inhibition Compared With Placebo for 5-Component Major Adverse Cardiac Events (rs1967309 Single-Nucleotide Polymorphism).
ACCELERATE indicates Assessment of Clinical Effects of Cholesteryl Ester Transfer Protein Inhibition with Evacetrapib in Patients at a High Risk for Vascular Outcomes; dal-OUTCOMES, dalcetrapib outcomes; HR, hazard ratio; OR, odds ratio.
aP value for heterogeneity of treatment effects across the genotypes, using the likelihood ratio test with 2° of freedom.
bTrend test performed after coding the genotypes as the number of minor alleles in the conditional logistic model and the corresponding genotype-by-treatment interaction tested.