Figure 2. Salience Network Connectivity.
A, Bilateral anterior insula seeds (coordinates in Montreal Neurological Institute space: left: -30, 18, 5; right: 34, 16, 5). B, Regions of the salience network (anterior insula seeds) that exhibited greater connectivity within the CVT as compared with RES and CTL groups as well as greater salience network connectivity with the superior frontal gyrus in the RES group. Color bar represents t values from the between-group paired t tests. B, Box-and-whisker plots of functional connectivity quantified as z scores for CTL, CVT, and RES groups. The horizontal line in the middle of each box indicates the median, while the top and bottom borders mark the 75th and 25th percentiles, respectively. The whiskers above and below the box mark the 90th and 10th percentile. The points beyond the whiskers are outliers. CTL indicates control; CVT, converted; and RES, high-risk resilient.
aP < .001 compared with CVT.
bP < .01 compared with CVT.