Table 1.
Ondansetron group (n=102) | Ramosetron group (n=104) | P-value | |
---|---|---|---|
Age (years) | 42.6±10.9 | 43.7±11.9 | 0.50 |
Women | 97 (95.1) | 96 (92.3) | 0.41 |
Body mass index (kg/m2) | 23.4±4.0 | 23.2±3.1 | 0.58 |
ASA physical status | 0.44 | ||
1 | 83 (81.4) | 79 (76.0) | |
2 | 20 (19.6) | 25 (24.0) | |
History of PONV or motion sickness | 38 (37.3) | 42 (40.4) | 0.65 |
Nonsmoking | 99 (97.1) | 100 (96.2) | 1.00 |
Simplified risk score | 0.78 | ||
2 | 10 (10.2) | 11 (10.6) | |
3 | 57 (55.9) | 59 (56.7) | |
4 | 35 (34.3) | 34 (32.7) | |
Duration of anesthesia (min) | 123.9±47.5 | 121.4±66.2 | 0.75 |
Duration of surgery (min) | 94.1±45.2 | 92.2±64.6 | 0.81 |
Duration of PACU stay (min) | 67.2±24.4 | 70.6±25.6 | 0.32 |
Use of fentanyl-based IV PCA | 70 (68.6) | 59 (56.7) | 0.08 |
Type of surgical procedure | 0.35 | ||
Cholecystectomy | 34 (33.3) | 43 (41.3) | |
Hysterectomy | 21 (20.6) | 18 (17.3) | |
Ovarian cystectomy | 19 (18.6) | 20 (19.2) | |
Myomectomy | 19 (18.6) | 13 (12.5) | |
Salpingo-oophorectomy | 6 (5.9) | 8 (7.7) | |
Other gynecologic surgery | 3 (2.9) | 2 (1.9) |
Note: Values are presented as mean ± standard deviation or number (%) of patients.
Abbreviations: ASA, American Society of Anesthesiologists; PONV, postoperative nausea and vomiting; PACU, postanesthesia care unit; IV PCA, intravenous patient-controlled analgesia.