Table 1.
Summary of agents tested, their EC50 values, Hill coefficient values, and their ability to generate a persistent current at 10μ M and −60 mV.
| Compounds | EC50 (μM) | Hill coefficients | Persistent Current |
| DA (2) | 1.35 ± 0.06 | 1.32 ±0.07 | No |
| R(−)AMPH (R1) | 1.31 ± 0.22 | 0.82 ±0.09 | No |
| S(+)AMPH (S1) | 1.25 ± 0.14 | 1.33 ±0.17 | Yes |
| 3-des-OH DA (3) | 1.43 ± 0.17 | 0.91 ±0.08 | No |
| 4-des-OH DA (4) | 0.96 ± 0.08 | 1.07 ±0.09 | No |
| β-PEA (5) | 3.47 ± 0.18 | 1.06 ± 0.16 | Yes |
| R(−) α-Me 3-des-OH DA (R6) |
2.25 ± 0.21 | 0.98 ± 0.08 | No |
| R(−) α-Me DA (R7) | 6.09 ± 0.52 | 0.55 ± 0.06 | No |
| S(+) α-Me 3-des-OH DA (S6) |
1.72 ± 0.38 | 0.49 ± 0.05 | No |
| S(+) α-Me DA (S7) | 1.45 ± 0.50 | 0.71 ± 0.11 | No |