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. 2018 Mar 25;8(3):e020455. doi: 10.1136/bmjopen-2017-020455

Table 3.

PPV and NPV, sensitivity, specificity for overall HF hospitalisation identification algorithm,* weighted analysis

Confirmed HF hospitalisation, sum weight† (n)‡ Confirmed non-HF hospitalisation, sum weight (n) Total hospitalisations, sum weight (n) Performance metric (95% CI)§
HF algorithm positive 513 (354) 59 (45) 572 (399) PPV 89.7 (86.8 to 92.7)
HF algorithm negative 624 (6) 9570 (92) 10 194 (98) NPV 93.9 (89.1 to 98.6)
Total 1138 (360) 9628 (137) 10 766 (497)
Validity measure Sensitivity (95% CI)
45.1 (25.1 to 65.1)
Specificity (95% CI)
99.4 (99.2 to 99.6)

*The HF algorithm consisted of a primary discharge diagnosis ICD-9 code 425.X, 428.X, 402.01, 402.11, 402.91, 404.01, 404.03, 404.11, 404.13, 404.91, 404.93 or 398.91 and/or a DRG code 127 or 291–293.

†Sum weight represents the number of hospitalisations from the overall study population that would have fallen into each category when inverse probability of sampling weights were applied to the study sample.

‡n represents the actual number of charts reviewed that were true positives, false positives, false negatives or true negatives in each category.

§To create 95% CIs, we used a Taylor series linearisation to calculate SEs with sampling weights.

DRG, diagnosis-related group; HF, heart failure; ICD-9, International Classification of Diseases Ninth Revision; NPV, negative predictive value; PPV, positive predictive value.